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The Middle East is a region of extreme climates including mountains and arid deserts. It was in Assyria, (now Iraq), that edible and medicinal plants were first brought into cultivation. "It is impossible to get a chart of the voyage," wrote an Italian agent concerning Cabral's expedition, "because the King has decreed the death penalty for anyone sending one abroad." It is also said that charts were sometimes only lent to navigators by the Portuguese India House and at the end of a voyage the chart had to be returned to that ... c.3400 B.C. The opium poppy is cultivated in lower Mesopotamia. The Sumerians refer to it as Hul Gil, the 'joy plant.' The Sumerians would soon pass along the plant and its euphoric effects to the ...